Nephritic changes of transgenic mice with high serum titer of anti-keratin autoantibody / 中华风湿病学杂志
Chinese Journal of Rheumatology
;
(12)2003.
Article
Dans Chinois
| WPRIM
| ID: wpr-683425
ABSTRACT
Objective To analyze the autoimmune status of kidney in transgenic mice with high serum titer of anti-keratin autoantibody(AK auto Ab).Methods AK auto-Ab transgenie mice were set-up with conventional procedures,and the mice older than 20 weeks were selected for study.Urinary protein was quan- tified by Bradford method,and SDS-PAGE electrophoresis was used to analyze the type of proteinuria.Speci- mens of kidney were subjected to HE and PAS stain and immunofluorescence analysis and electrum microscopy observation were also performed.Results Compared with littcrmates,transgenie mice showed higher urinary proteins level(P
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
Chinese Journal of Rheumatology
Année:
2003
Type:
Article
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