Expression of adhesion molecules in polymyositis / 医学研究生学报
Journal of Medical Postgraduates
;
(12)2003.
Article
Dans Chinois
| WPRIM
| ID: wpr-684344
ABSTRACT
Objective:
To study the role of adhesion molecules in the pathogenesis of polymyositis.Methods:
The abnormal expression of adhesion molecules on T cells in peripheral blood and muscle fibers from patients with myositis was analyzed by two colour immunofluoresence and RT PCR methods respectively.Results:
The expression of adhesion molecules including lymphocyte function associated antigen 1(LFA 1 ),very late antigen 4(VLA 4) on T cells in peripheral blood and intercellular adhesion molecule l(ICAM 1) on muscle fibers from patients with myositis was markedly higher than that in the healthy control group.Conclusion:
These findings suggested that adhesion molecules may be responsible for the migration of T cells and destraction of muscle fibers.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
Journal of Medical Postgraduates
Année:
2003
Type:
Article
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