THE IMPACT OF FRAMESHIFT MUTAIONS WITHIN mhbR AND mhbT ON THE CATABOLISM OF 3-HYDROXYBENZOATE / 微生物学通报
Microbiology
; (12)1992.
Article
de Zh
| WPRIM
| ID: wpr-684454
Bibliothèque responsable:
WPRO
ABSTRACT
Klebsiella pneumoniae M5a1 metabolizes 3-hydroxybenzoate via gentisate to central metabolites. The plasmid pBSI encoding the full catabolic pathway endowed E.coli with the ability to grow on 3-hydroxybenzoate. We have determined the sequence of an 8-kb region spanning the mhb genes. Blast search in the GenBank revealed the mhbR was a putative transcript regulator and mhbT was a putative 3-hydroxybenzoate transporter. The E.coli strain containing the plasmid with frameshift mutantion either in mhbR or mhbT grew more slowly on 3-hydroxybenzoate than that containing the wild type clone.
Texte intégral:
1
Indice:
WPRIM
langue:
Zh
Texte intégral:
Microbiology
Année:
1992
Type:
Article