Study on Degradation of Oxidized Regenerated Cellulose Absorbable Hemostatic Products / 中国医疗器械杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the degradation of oxidized regenerated cellulose absorbable hemostatic products.</p><p><b>METHODS</b>The morphology of the oxidized regenerated cellulose hemostatic products before and after degradation was observed by FTIR and SEM. The degradation products were determined by GPC and HILIC-ELSD.</p><p><b>RESULTS</b>In the initial stage of degradation, there was a great change in morphology. GPC determined its degradation end point was 10 d; it was determined that its degradation products contained glucose (0.13%) and cellobiose (0.17%) and other components.</p><p><b>CONCLUSIONS</b>A method was established for determining the end point of degradation of oxidized regenerated cellulose, which provided a new idea and reference for the study of the degradation end point.</p>