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IgG4-Related Tubulointerstitial Nephritis Accompanied by Henoch-Schonlein Purpura / 대한내과학회지
Korean Journal of Medicine ; : 96-100, 2014.
Article Dans Coréen | WPRIM | ID: wpr-69085
ABSTRACT
Tubulointerstitial nephritis is one of the common manifestations of immunoglobulin G (IgG)4-related disease; however, among all cases of tubulointerstitial nephritis undergoing renal biopsies, IgG4-related tubulointerstitial nephritis seems to be relatively rare because of its trivial urinary findings. A previously healthy 54-year-old man was referred to our clinic with a 4-week history of lower leg purpura and renal dysfunction. A kidney biopsy was planned because of bilateral renomegaly, by imaging studies, and elevated serum creatinine levels. Pathological findings in the kidney showed prominent infiltration of IgG4-postive plasma cells in the tubulointerstitium, but not the glumeruli. A skin biopsy revealed leukocytoclastic vasculitis, accompanied by deposition of IgA and C3 in the vascular wall, indicating Henoch-Schonlein purpura (HSP). Although cases of combined IgG4-related disease and microvasculitis, including HSP, are extremely rare, the possibility of an association between two diseases deserves attention.
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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Plasmocytes / Purpura / / Peau / Vascularite / Biopsie / Immunoglobuline A / Immunoglobuline G / Créatinine / Rein Limites du sujet: Humains langue: Coréen Texte intégral: Korean Journal of Medicine Année: 2014 Type: Article

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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Plasmocytes / Purpura / / Peau / Vascularite / Biopsie / Immunoglobuline A / Immunoglobuline G / Créatinine / Rein Limites du sujet: Humains langue: Coréen Texte intégral: Korean Journal of Medicine Année: 2014 Type: Article