Effect evaluation on application of gallnut extract in root canal therapy of patients with chronic periapical periodontitis / 吉林大学学报(医学版)

ABSTRACT

Objective:To explore the influence of gallnut extract as a root canal irrigants in the curative effect of chronic periapical periodontitis,and to clarify its mechanism.Methods:A total of 192 patients diagnosed with chronic periapical periodontitis were selected and randomly divided into control group (distilled water),hydrogen peroxide group,sodium hypochlorite group and gallnut extract group (n=48).In the process of root canal treatment,four irrigants were used respectively,then the curative effects 1 week,6 months,12 months after treatment were observed and compared.Results:After root filling treatment,the cold and heat stimulation of the tooth was insensitive in clinical examination,percussion (-),loose degree≤ Ⅰ °,no swollen gums,bleeding on probing (-),no fistula,normal function of the exercise of chewing,decreased or disappeared transmission area in periapical bone in X-ray photo,and those metioned above were considered effective treatment.After 6 months oftreatment,the effective rate in gallnut group was 89.4％,and there were no statistically significant differences compared with hydrogen peroxide group (91.1％) and sodium hypochlorite group (91.5 ％) (P＞0.05),but there was significant difference compared with control group (67.4％) (P＜0.05).After root filling treatment for 12 months,the effective rate in gallnut group was 83.7％ and there were no statistically significant differences compared with hydrogen peroxide group (83.3％)and sodium hypochlorite group (87.8％) (P＞0.05),but the ratio of tooth from improvement to recovery in gallnut group was higher than those in hydrogen peroxide group and sodium hypochlorite group.Conclusion:Gallnut extract as a root canal irrigants has good antibacterial and cleaning effect,and can achieve the aim of curing the chronic root periapical inflammation and preventing the infection.