Role of tryptophan catabolism in pediatric allergic diseases / 国际儿科学杂志
International Journal of Pediatrics
;
(6): 153-155, 2018.
Article
Dans Chinois
| WPRIM
| ID: wpr-692460
ABSTRACT
With the change of environment and life-style,the incidence of allergic diseases in children is increasing,but its pathogenesis is not entirely elucidated.It is shown that tryptophan catabolism mediated by indoleamine 2,3-dioxygenase plays a significant role in the pathophysiology of allergic diseases of children such as asthma and allergic rhinitis.These roles include inducing Treg cell,inhibiting Th2 cell response,mediating immune tolerance and so forth.Therefore,it is a new target for the prevention and treatment of allergic diseases by stimulating the immune cells and changing the diet structure to regulate tryptophan catabolism.This article reviews the role of tryptophan decomposition in children allergic diseases.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
International Journal of Pediatrics
Année:
2018
Type:
Article
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