Research progress of CfDNA quantitative analysis for malignant solid tumors in children / 国际儿科学杂志

ABSTRACT

Circulating free DNA is DNA fragments in the blood,mainly from cell apoptosis,necrosis and release.Its content is significantly different in the bood of healthy human and malignant tuimor patients,which is associated with tumor characteristics.This review will summarize the research progress of CfDNA quantitative analysis for malignant solid tumor and prospect the application value for children's solid tumors.