Disorders of sex development and factors related to sexual differentiation / 国际儿科学杂志

ABSTRACT

Human sexual differentiation is mainly manifested in behavior and brain development,which embodied in gender identity,gender role,sexual orientation and cognitive ability. Patients with disorders of sex development who show abnormal sex behavior provide a unique perspective for the study of sexual differentia-tion. Studies have found the main factors that affect sexual differentiation including sex chromosomes,sex hor-mones and social psychological factors. The influencing degree of these three factors is different,and there are strong interactions within them. Moreover,the development of medical imageology has led to a better understand-ing of the sexual differences in brain structure and cognitive ability. At present,the studies of human sexual dif-ferentiation are scarce,and the objects of these studies mainly focus on patients with disorders of sex develop-ment. This paper reviews the recent studies on disorders of sex development and factors related to sexual differ-entiation.