Determination and analysis of serum specific IgE in patients with allergic diseases in Shenzhen area / 国际检验医学杂志

ABSTRACT

Objective To analyze the specific IgE test results and the distribution of allergens in patients with allergic diseases in Shenzhen area .Methods Western blot was used to detect inhaled and food specific IgE in 2154 patients with allergic diseases ,and the types and distribution of allergens were analyzed .Results The total positive rate of allergen specific IgE was 48 .88％ .More than 20％ of the patients were allergic to more than two allergens .The most common allergies were dust mites ,freshwater fish and sea fish .The posi-tive rate of IgE in male allergens was higher than that in females ,and the difference was statistically signifi-cant (P<0 .05) .The positive rate of allergen specific IgE in different age groups was statistically significant (P<0 .001) .The positive rate of dust mites increased year by year before the age of 18 ,and then decreased year after year .The positive rate of chicken protein and milk showed a significant downward trend after 7 years old .The positive rate of allergen IgE in patients with different diseases was statistically significant (P<0 .001) .The positive rate of dust mite combination in rhinitis patients was the highest ,49 .94％ .Conclu-sion The main allergen of allergic diseases in Shenzhen area is dust mites combination ,freshwater fish com-bination and sea fish combination .The main food allergen of children is egg and milk .The main allergen of a-dult is dust mites combination and fish ,and the patients with rhinitis are high sensitized people of dust mites combination .