Antitumor effect and mechanism of tropolones / 国际药学研究杂志

ABSTRACT

Tropolones,non-benzenoid aromatic compounds with a seven-numbered-ring structure,are mainly found in the secondary metabolites of fungi.Tropolones are characterized by the antibacterial,antifungal,antiviral,anti-inflammatory,insecticidal, and antitumor activities.Antitumor effect has been extensively explored in recent years,but so far there is still no ideal antitumor drug-candidates obtained from these compounds.The research progress of antitumor effect and mechanism of tropolones are reviewed in this paper for a reference for the future.