Diagnosis and treatment of recurrent high grade glioma / 国际肿瘤学杂志

ABSTRACT

High grade glioma is a kind of malignant brain tumor with strong invasiveness,which progresses commonly after initial treatments and shows high mortality.Early diagnosis of tumor recurrence and highly-individualized systemic treatment mean significance to prolong survival.Multi-mode magnetic resonance imaging and molecular imaging play important roles in differential diagnosis and prognosis evaluation for recurrence.Therapeutic strategies like re-operation,re-irradiation,electric field technology,chemotherapy,targeted therapies and immunotherapeutic approaches are expected to bring survival benefits for patients with recurrent high grade glioma.