The effect of partial splenic embolization on the hemodynamics of splenic and portal venous pressure / 介入放射学杂志

ABSTRACT

Objective To investigate the changes of splenic and portal venous pressure after partial splenic embolization (PSE),and to discuss its influence factors.Methods PSE was carried out in 14 patients with portal hypertension complicated by hypersplenism.Before and after PSE,the splenic and portal vein pressure was determined by direct manometry method.The post-operative venous pressure was compared with pre-operative one.Contrast-enhanced CT scan was performed 1-2 months after the treatment.Results After PSE,the splenic venous pressure was decreased obviously,a reduction of more than 2 cmH2O in portal venous pressure was observed in 7 patients.Post-operative reexamination with contrast-enhanced CT scan showed that varying degrees of improvement of esophageal and gastric varices could be observed in most patients.Conclusion PSE can effectively decrease the splenic venous pressure,and there are a lot of factors that may influence the short-term reduction in portal vein pressure.