Rethink and Understanding of the Concept and Diagnostic Criteria of Lymphoma——Presentation of the Concept of "Low-Grade Malignant Potential Lymphoid Neoplasms" / 现代检验医学杂志

ABSTRACT

Some monoclonal lymphoid tissue lesions showing benign biological behavior have been found recently,they usually were diagnosed with lymphoma,their malignant potential is extremely limited and almost does not develop.However,it presents a challenge to the concept of lymphoma and its diagnostic standard.Based on this,the auther propose the concept of "benign lymphoma" at the theoretical level,and discusses the possibility of its existence from two aspects of clonality and lymphocyte fluidity.At the same time,based on clinical practice and diagnostic strategies,propose the " Low-grade malignant potential lymphoid neoplasms "diagnostic terms for the first time,on the one hand,it show that this type of lesion is different from lymphoma and avoids overt reatment,on the other hand,clinicians and patients were reminded to follow up observation to prevent recurrence of a small number of cases,so as to trigger the discussion on the biological essence of lymphoma.