Pediatric pulmonary alveolar proteinosis / 中华实用儿科临床杂志

ABSTRACT

Pulmonary alveolar proteinosis is a rare disease in children.The accumulation of massive amount of lipid and protein in the alveolar can lead to the progressive dyspnea and hypoxemia.The diagnosis could be made with the high resolution computed tomography and pathological findings.Appropriate treatments according to the pathogenesis,together with whole lung lavage,can significantly improve disease outcome.This article will provide a review of the pathogenesis,clinical features,therapeutic approach and disease prognosis of pediatric pulmonary alveolar proteinosis.