Evaluating the effect and safety of treating thyroid multiple-nodule by Ultrasound-guided microwave ablation in one-session / 实用医学杂志

ABSTRACT

Objective To investigate the short-term efficacy of treating thyroid multiple-nodule by Ultrasound-guided microwave ablation in one-session,and to evaluate its safety and effect.Methods Treatment and follow-up data of 85 patients with benign thyroid nodules underwent tUltrasound-guided microwave ablation in one-session were retrospectively analyzed.Results Symptom scores and cosmetic scores increased with the increasing number of nodules ablated before ablation (P ＜ 0.001),as well as the ablation time (P ＜ 0.001).However,there was no significant difference in the amount of isolation belt and intraoperative pain score between the groups.There were no serious complications such as recurrent laryngeal nerve injury and massive hemorrhage in 85 cases underwent tUltrasound-guided microwave ablation in one-session.Compared with the thyroid function,there was no significant difference on before the ablation and 1,3,6 months after ablation.Postoperative 6 months,the maximum volume of nodule and the total volume of the nodules were reduced 63％ and 69.5％,respectively.After ablation,both the symptom scores and cosmetic scores were improved significantly.On 6 months after ablation,the symptom scores decreased from (4.41 ± 1.75) cm to (1 ± 0.76) cm,and the cosmetic score3 decreased from 2.27 ± 0.81 to 1.25 ± 0.43.Conclusion Ultrasound-guided microwave ablation could treat multiple thyroid nodules effectively and protect the physiological function of thyroid,which was worthy of further promotion in clinical application.