Research progress and clinical significance of QKI protein in malignant tumor / 实用肿瘤学杂志

ABSTRACT

QKI protein is a kind of STAR protein family and mainly contains three subtypes of QKI-5,QKI-6 and QKI-7. Early studies showed that QKI protein is closely related to the development of nerve myelin and embryo. With the development of molecular biology and the extensive application of gene technology,the effect of QKI protein on malignant tumors has received increas-ing attention. The studies of QKI protein from lung,gastric and prostate cancers have shown that it has the ability to inhibit tumor inva-sion,and may become a new target for the diagnosis and treatment of malignant tumors. Although significant progress has been made in the extensive research of QKI protein in malignant tumors,there are still many doubtful points that need to be answered. Thus,further research and exploration of QKI are needed in malignant tumor.