Advances in Diagnosis and Treatment of Autoimmune Hepatitis / 胃肠病学

ABSTRACT

Autoimmune hepatitis (AIH)is a chronic progressive immune-mediated inflammatory liver disease. Both adults and children could be involved and women are more often affected. AIH is characterized by elevation of serum IgG/hypergammaglobulinemia,autoantibodies and interface hepatitis with diverse clinical spectrum. The incidence of AIH is increasing in recent years. If not treated timely,it may lead to cirrhosis and liver failure. Immunosuppressive therapy is crucial for improving patients'survival rate. This article summarized the advances in diagnosis and treatment of AIH.