Three-dimensional simulation and simulated mechanical test of individual femoral prosthesis / 中国组织工程研究

ABSTRACT

BACKGROUND: A study combined medical CT technology and digital three-dimensional (3D) interactive control system Mimics software and computer simulation software tools for 3D reconstruction and simulation reconstruction of the femur. Customized individualized femoral prosthesis has high matching degree with human body structure, and has high application value in clinical research. OBJECTIVE: To investigate the application value of 3D simulation of femoral prosthesis in artificial femoral prosthesis replacement. METHODS: Totally 82 cases, who received femoral prosthesis replacement from July 2014 to June 2016 in Taihe Hospital of Shiyan, were enrolled and randomly assigned to three groups personalized group (n=28), cementless group (n=27) and cemented group (n=27). Different types of femoral prosthesis were designed in each group. 3D model reconstruction in femur was designed using medical CT technology combined with computer. Prosthesis implantation was simulated in computer, and the relevant information was recorded. Simulated operation was conducted on the mechanical experiment of femoral prosthesis in the biped and single foot loads so as to provide the most suitable operation plan. The possible risk was forecasted and assessed for preoperative preparation. RESULTS AND CONCLUSION: (1) In the simulation of mechanical experiment, under double foot and single foot loads, after prosthetic replacement, stress in the femur was significantly better in the personalized group than in the cementless group and cemented group (P <0.05). (2) After replacement, normal stress and shear stress were significantly better in the personalized group than in the cementless group and cemented group (P < 0.05). (3) The initial, horizontal and vertical micromovement was significantly better in the personalized group than in the cementless group and cemented group (P < 0.05). (4) In summary, the use of computer technology and 3D CT software can make individualized femoral prosthesis for patients. Compared with the cementless and cemented prostheses, personalized prosthesis has obvious advantages in stress distribution, interface stress and initial micromovement.