Analysis of Risk Factors for Mortality from Acute Paraquat Poisoning / 中国医科大学学报

ABSTRACT

Objective To analyze risk factors for mortality from acute paraquat poisoning. Methods A retrospective study was performed that included 162 patients with acute paraquat poisoning who visited the emergency room between January 2016 and July 2017. The patients were divided into survival and non-survival groups, and paraquat doses and regular laboratory test results were recorded. The significantly different parameters (P ＜ 0. 05) that were identified between the two groups were included in logistic regression analyses to identify independent risk factors of mortality, and receiver-operating characteristic curves were generated to evaluate the prognostic ability of each risk factor. Results Paraquat dose, hemoperfusion, blood lactic acid level, serum creatinine level, and urine paraquat concentration were independent risk factors for mortality from acute paraquat poisoning (P ＜ 0. 05). Conclusion Paraquat dose, hemoperfusion, blood lactic acid, serum creatinine, and urine paraquat concentration can be used to determine the prognosis of acute paraquat poisoning.