Research progress of human glioma angiogenesis / 中国医师杂志

ABSTRACT

Tumor angiogenesis is the important pathophysiological characteristics of human glioma.The treatment of tumor angiogenesis is currently a hot research topic.This article reviewed the domestic and international research on angiogenesis of glioma,included animal models,cellular mechanisms,regulatory factors,signaling pathways,antiangiogenic drugs,and proteomics regarding glioma angiogenesis to clarify the current status of research and clinical treatment,providing reference for further study on angiogenesis of glioma,and discovery of novel biomarkers of tumor angiogenesis and therapeutic targets.