Research progress in imaging agents targeting Aβ and Tau protein in Alzheimer's disease / 中华核医学与分子影像杂志

ABSTRACT

Alzheimer's disease (AD) is a neurodegenerative disease,which is insidious onset and progressive.The pathological features of AD include senile plaques composed of amyloid β (Aβ) and neurofibrillary tangles composed of Tau protein.Aβ and Tau protein targeted imaging agents,which make a non-invasive and high specificity diagnosis,might be useful for early diagnosis,efficacy monitoring and drug evaluation for AD.This review summarizes the progress and clinical applications of those agents in AD.