Advances in exosomal microRNA and pathogenesis of preeclampsia / 中华围产医学杂志
Chinese Journal of Perinatal Medicine
;
(12): 622-625, 2018.
Article
Dans Chinois
| WPRIM
| ID: wpr-711226
ABSTRACT
Preeclampsia is an idiopathic gestational disease with unknown etiology or pathogenesis. Exosomes are membranous nanovesicles secreted by various cells, carrying contents such as proteins, mRNA, microRNA and lipids and being involved in regulations between cells by transporting the above contents through target cells. The expression of exosome-derived proteins and microRNAs in preeclampsia patients experiences changes, resulting in maternal inadequate trophoblast invasion, depressed endothelial cell function and angiogenesis. Research on placenta-derived exosomal microRNAs in preeclampsia patients may help to elucidate the pathogenesis of preeclampsia.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Type d'étude:
Etude d'étiologie
langue:
Chinois
Texte intégral:
Chinese Journal of Perinatal Medicine
Année:
2018
Type:
Article
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