The Changes in Corneal Astigmatism after Botulinum Toxin-A Injection in Patients with Blepharospasm
Journal of Korean Medical Science
; : 131-135, 2006.
Article
Dans En
| WPRIM
| ID: wpr-71340
Responsable en Bibliothèque :
WPRO
ABSTRACT
To determine if the involuntary contractions of eyelids may have any effects on the development of corneal astigmatism, we performed this prospective study which includes 19 patients with either essential blepharospasm or hemifacial spasm. In hemifacial spasm, the degree of corneal astigmatism was evaluated between two eyes. Then the topographic changes were checked using vector analysis technique before and after passively opening the eyelids. They were also measured before and at 1 and 6 months after the injection of Botulinum toxin. Resultantly, 20 eyes had the with-the-rule (group1) and 9 eyes against-the-rule (group2) astigmatism. In hemifacial spasm, significantly more astigmatism was found at spastic eyes. The corneal topographic changes after passively opening the eyelids showed 10 eyes with the astigmatic shift to the with-the-rule, while the remaining 19 to the againstthe- rule. At 1 month after injection of Botulinum toxin, group 1 showed reduced average corneal astigmatism, whereas group 2 showed increased astigmatism. The astigmatic change vector showed significantly more against-the-rule. In the contrary, 6 months after treatment, corneal astigmatism again increased in group 1 and decreased in group 2. So they took on the appearance of pretreatment astigmatic status eventually. Conclusively eyelids may play an important role in corneal curvature.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Astigmatisme
/
Facteurs temps
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Blépharospasme
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Résultat thérapeutique
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Toxines botuliniques de type A
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Cornée
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Maladies de la cornée
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Paupières
/
Injections
Type d'étude:
Observational_studies
Limites du sujet:
Aged
/
Female
/
Humans
/
Male
langue:
En
Texte intégral:
Journal of Korean Medical Science
Année:
2006
Type:
Article