The Role of B Cells in Transplantation Rejection / 대한이식학회지
The Journal of the Korean Society for Transplantation
;
: 1-6, 2018.
Article
Dans Anglais
| WPRIM
| ID: wpr-713610
ABSTRACT
B cells play a role in graft rejection via several mechanisms. Specifically, B cells produce high-affinity antibodies to alloantigens including allogeneic major histocompatibility complex (MHC) with the help of follicular helper T cells. B cells also function as antigen-presenting cells for alloreactive T cells, resulting in the activation of alloreactive T cells. Conversely, the frequency of regulatory B cells increases under inflammatory conditions and suppresses the rejection process. Here, the differential roles of the major B cell subpopulations (B-1, follicular B, marginal zone B, and regulatory B cells) involved in transplantation rejection are discussed together with their interaction with T cells.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Lymphocytes B
/
Lymphocytes T
/
Lymphocytes T auxiliaires
/
Lymphocytes B régulateurs
/
Rejet du greffon
/
Isoantigènes
/
Complexe majeur d'histocompatibilité
/
Anticorps
/
Diversité des anticorps
/
Cellules présentatrices d'antigène
langue:
Anglais
Texte intégral:
The Journal of the Korean Society for Transplantation
Année:
2018
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS