Verification of a Western Nomogram for Predicting Oncotype DX™ Recurrence Scores in Korean Patients with Breast Cancer / 한국유방암학회지
Journal of Breast Cancer
;
: 222-226, 2018.
Article
Dans Anglais
| WPRIM
| ID: wpr-714859
ABSTRACT
A recent study conducted at the University of Tennessee Medical Center using a large dataset from the National Cancer Database (NCDB) reported the use of nomograms for predicting Oncotype DX™ (ODX) scores with clinicopathologic data. We reviewed the data of 218 patients who underwent the ODX test at a single institution in Korea to confirm that nomograms can accurately predict ODX score groups using our data, which differ from those of the NCDB in terms of ethnicity. The concordance index (c-index) of nomograms was much lower than that of the University of Tennessee Medical Center for high- and low-risk groups of commercial ODX and Trial Assigning Individualized Options for Treatment values. Although the nomogram for predicting ODX scores was based on a large dataset, it could not be generalized to patients in Asia. Further studies using large datasets of patients from different ethnicities should be performed to develop a nomogram applicable to patients worldwide.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Asie
/
Récidive
/
Région mammaire
/
Tumeurs du sein
/
Ethnies
/
Tennessee
/
Nomogrammes
/
Ensemble de données
/
Corée
Type d'étude:
Étude pronostique
Limites du sujet:
Humains
Pays comme sujet:
Amérique du Nord
/
Asie
langue:
Anglais
Texte intégral:
Journal of Breast Cancer
Année:
2018
Type:
Article
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