Relationship between Autistic Spectrum Trait and Regional Cerebral Blood Flow in Healthy Male Subjects
Psychiatry Investigation
;
: 956-961, 2018.
Article
Dans Anglais
| WPRIM
| ID: wpr-717823
ABSTRACT
OBJECTIVE:
Autistic spectrum traits are postulated to lie on a continuum that extends between individuals with autism and individuals with typical development. The present study was carried out to investigate functional and network abnormalities associated with autistic spectrum trait in healthy male subjects.METHODS:
Subjects were 41 healthy male subjects who underwent the social responsiveness scale-adult (SRS-A) and magnetic resonance imaging.RESULTS:
There was significant positive correlation between the total score of SRS-A and the regional cerebral blood flow (CBF) in posterior cingulate cortex (PCC). Also, there were changes in functional network such as in cingulate corti, insula and fusiform cortex. Further, we also found the significant difference of functional networks between the healthy male subjects with high or low autistic spectrum trait, and these points were congruent with the previous perceptions derived from autistic-spectrum disorders.CONCLUSION:
These findings suggest a biological basis for the autistic spectrum trait and may be useful for the imaging marker of autism symptomatology.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Trouble autistique
/
Imagerie par résonance magnétique
/
Substances à réaction différée de l'anaphylaxie
/
Circulation cérébrovasculaire
/
Trouble du spectre autistique
/
Gyrus du cingulum
Limites du sujet:
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Psychiatry Investigation
Année:
2018
Type:
Article
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