Mutation of the N-ras Gene in a Patient Suffering from the Blast Phase of Chronic Myelogenous Leukemia
Korean Journal of Hematology
;
: 100-103, 2009.
Article
Dans Coréen
| WPRIM
| ID: wpr-720044
ABSTRACT
The blast phase in chronic myelogenous leukemia (CML) is associated with mutation of several genes. It is well known that p53 gene mutation plays a key role in the myeloid or lymphoid blast phase of CML. But for the case of the N-ras gene, the association between N-ras mutations and the blast phase of CML is not yet known. We report here on a case of detecting N-ras point mutation without p53 mutation in a 64 year-old man who suffered from the lymphoblastic blast phase of CML.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Stress psychologique
/
Leucémie myéloïde chronique BCR-ABL positive
/
Crise blastique
/
Gènes p53
/
Gènes ras
/
Mutation ponctuelle
Limites du sujet:
Humains
langue:
Coréen
Texte intégral:
Korean Journal of Hematology
Année:
2009
Type:
Article
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