Generalized Primary Amyloid Lymphadenopathy
Korean Journal of Hematology
;
: 320-324, 2009.
Article
Dans Anglais
| WPRIM
| ID: wpr-721041
ABSTRACT
Systemic amyloidosis is a disease that displays deposition of insoluble polymeric protein fibrils in tissues and organs. We report here on a case of a 64-year-old woman who initially presented with multiple enlarged lymph nodes. Computed tomography showed multiple enlarged lymph nodes in the mediastinal, lower cervical, supraclavicular, axillary and abdominal areas. Excision biopsy of the cervical lymph nodes and the subsequent histopathology showed amorphous eosinophilic material deposits, and these revealed apple-green birefringence on a polarizing microscopic examination on the Congo-red stained slide. The patient was diagnosed with amyloidosis and she received chemotherapy consisting of melphalan and dexamethasone. During chemotherapy, she was diagnosed with breast cancer. After modified unilateral radical mastectomy, the dexamethasone was restarted and this therapy resulted in stable disease.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Polymères
/
Biopsie
/
Biréfringence
/
Tumeurs du sein
/
Dexaméthasone
/
Mastectomie radicale
/
Granulocytes éosinophiles
/
Amyloïde
/
Amyloïdose
/
Noeuds lymphatiques
Limites du sujet:
Femelle
/
Humains
langue:
Anglais
Texte intégral:
Korean Journal of Hematology
Année:
2009
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS