The Effect of Midodrine on Exercise-induced Hypotension in Cervical Cord Injury Patients
Journal of the Korean Academy of Rehabilitation Medicine
;
: 45-50, 2008.
Article
Dans Coréen
| WPRIM
| ID: wpr-722710
ABSTRACT
OBJECTIVE:
To evaluate the effect of midodrine, an alpha(1) agonist, on symptom and hemodynamic response during standing and arm bicycle ergometer exercise in patients with cervical cord injury.METHOD:
Twelve cervical spinal cord injury patients with orthostatic hypotension symptoms and post-exercise hypo- tension were enrolled. They were positioned on a 90degrees standing frame for 3 minutes. After 15 minutes of resting on supine position, 5 minutes of arm bicycle ergometer exercise was done. These tests were done without midodrine initially, but, with 5 mg midodrine on the next day. Heart rate, self-perceived presyncope score (PPS), systolic and diastolic blood pressure were measured before, during and after the exercise.RESULTS:
With 5 mg midodrine, the decrease of systolic and diastolic blood pressures after 3 minutes' standing was significantly smaller than without midodrine (p<0.05). PPS was also significantly decreased with midodrine on standing frame test. Arm ergometer exercise induced less systolic blood pressure decrease and better PPS on immediate and 5 minutes after exercise with midodrine (p<0.05). The change of diastolic blood pressure and heart rate was not significant after the exercise with midodrine.CONCLUSION:
In cervical spinal cord injury patients with orthostatic and post-exercise hypotension, 5 mg midodrine significantly improved the symptoms and the systolic blood pressures.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Bras
/
Traumatismes de la moelle épinière
/
Syncope
/
Pression sanguine
/
Décubitus dorsal
/
Hypotension post-exercice
/
Rythme cardiaque
/
Hémodynamique
/
Hypotension artérielle
/
Hypotension orthostatique
Limites du sujet:
Humains
langue:
Coréen
Texte intégral:
Journal of the Korean Academy of Rehabilitation Medicine
Année:
2008
Type:
Article
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