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Reticulocytosis in screen-printing workers exposed to 2-butoxyethanol and 2-ethoxyethanol
Annals of Occupational and Environmental Medicine ; : 54-2017.
Article Dans Anglais | WPRIM | ID: wpr-72426
ABSTRACT

BACKGROUND:

Studies on the hematologic toxicity of ethylene glycol ethers in humans are limited. Therefore, the aim of this study was to examine the association between exposure to solvents (containing 2-butoxyethanol and 2-ethoxyethanol) and hematological effects.

METHODS:

Thirty-four screen-printing workers who were exposed to 2-butoxyethanol and 2-ethoxyethanol and 37 non-exposed clerical workers were selected using data from the health care facilities that provided regular health screening services. Student's t-tests and Pearson's chi-square tests were used to compare differences in hematological parameters between the exposed and the control groups. A multivariate analysis was performed using the multiple logistic regression models to adjust for other variables.

RESULTS:

The chi-square test showed the reticulocyte percentages and corrected reticulocyte counts to be significantly higher in the exposed group. The t-tests showed a significant increase in white blood cell counts, reticulocyte percentages, and corrected reticulocyte count (i.e., reticulocyte index) in the exposed group, with p-values of 0.002, 0.004, and 0.002, respectively. Multivariate analysis showed the odds ratio for the corrected reticulocyte counts to be 16.30 for the exposed group, when compared with that of the control group.

CONCLUSIONS:

Exposure to 2-butoxyethanol and 2-ethoxyethanol was significantly associated with reticulocytosis, necessitating the implementation of preventive measures for workers prone to occupational exposure to ethylene glycol ethers.
Sujets)

Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Réticulocytes / Solvants / Modèles logistiques / Odds ratio / Dépistage de masse / Analyse multifactorielle / Exposition professionnelle / Clergé / Numération des réticulocytes / Éthylène glycol Type d'étude: Etude d'étiologie / Étude pronostique / Facteurs de risque / Étude de dépistage Limites du sujet: Humains langue: Anglais Texte intégral: Annals of Occupational and Environmental Medicine Année: 2017 Type: Article

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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Réticulocytes / Solvants / Modèles logistiques / Odds ratio / Dépistage de masse / Analyse multifactorielle / Exposition professionnelle / Clergé / Numération des réticulocytes / Éthylène glycol Type d'étude: Etude d'étiologie / Étude pronostique / Facteurs de risque / Étude de dépistage Limites du sujet: Humains langue: Anglais Texte intégral: Annals of Occupational and Environmental Medicine Année: 2017 Type: Article