Management of Obesity in Patients with Diabetes Mellitus / 임상당뇨병

ABSTRACT

Both obesity and diabetes impose not only individual health problems, but also large socioeconomic burdens worldwide. Obesity is a major cause of insulin resistance and diabetes and is closely linked to a series of microvascular and macrovascular complications that ultimately lead to increased morbidity and mortality. According to recent national survey data in Korea, obesity affects about 50% of adults with type 2 diabetes mellitus. Given the evidence that anti-obesity management has been beneficial in the treatment for patients with type 2 diabetes mellitus and obesity, providers should establish a strategy for weight loss for optimal, comprehensive patient management. Lifestyle intervention including diet and exercise is the cornerstone of prevention and management for obesity and type 2 diabetes mellitus. Anti-obesity drugs should be provided to those who do not respond appropriately to lifestyle intervention. Emerging data support the superiority of metabolic surgery over lifestyle or medical management for the management of type 2 diabetes associated with severe obesity. This article concisely reviews the current recommendation for lifestyle intervention including diet and exercise and pharmacological and surgical methods for obesity management in type 2 diabetic patients.