Blood flow in intracranial aneurysms treated with Pipeline embolization devices: computational simulation and verification with Doppler ultrasonography on phantom models
Ultrasonography
;
: 98-108, 2015.
Article
Dans Anglais
| WPRIM
| ID: wpr-731107
ABSTRACT
PURPOSE:
The aim of this study was to validate a computational fluid dynamics (CFD) simulation of flow-diverter treatment through Doppler ultrasonography measurements in patient-specific models of intracranial bifurcation and side-wall aneurysms.METHODS:
Computational and physical models of patient-specific bifurcation and sidewall aneurysms were constructed from computed tomography angiography with use of stereolithography, a three-dimensional printing technology. Flow dynamics parameters before and after flow-diverter treatment were measured with pulse-wave and color Doppler ultrasonography, and then compared with CFD simulations.RESULTS:
CFD simulations showed drastic flow reduction after flow-diverter treatment in both aneurysms. The mean volume flow rate decreased by 90% and 85% for the bifurcation aneurysm and the side-wall aneurysm, respectively. Velocity contour plots from computer simulations before and after flow diversion closely resembled the patterns obtained by color Doppler ultrasonography.CONCLUSION:
The CFD estimation of flow reduction in aneurysms treated with a flow-diverting stent was verified by Doppler ultrasonography in patient-specific phantom models of bifurcation and side-wall aneurysms. The combination of CFD and ultrasonography may constitute a feasible and reliable technique in studying the treatment of intracranial aneurysms with flow-diverting stents.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Simulation numérique
/
Angiographie
/
Endoprothèses
/
Anévrysme intracrânien
/
Échographie
/
Échographie-doppler couleur
/
Échographie-doppler
/
Procédures endovasculaires
/
Hydrodynamique
/
Anévrysme
Type d'étude:
Etude diagnostique
langue:
Anglais
Texte intégral:
Ultrasonography
Année:
2015
Type:
Article
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