Odor-Dependent Hemodynamic Responses Measured with NIRS in the Main Olfactory Bulb of Anesthetized Rats
Experimental Neurobiology
;
: 189-196, 2011.
Article
Dans Anglais
| WPRIM
| ID: wpr-73123
ABSTRACT
In this study, we characterize the hemodynamic changes in the main olfactory bulb of anesthetized Sprague-Dawley (SD) rats with near-infrared spectroscopy (NIRS, ISS Imagent) during presentation of two different odorants. Odorants were presented for 10 seconds with clean air via an automatic odor stimulator. Odorants are (i) plain air as a reference (Blank), (ii) 2-Heptanone (HEP), (iii) Isopropylbenzene (IB). Our results indicated that a plain air did not cause any change in the concentrations of oxygenated (Delta[HbO2]) and deoxygenated hemoglobin (Delta[Hbr]), but HEP and IB induced strong changes. Furthermore, these odor-specific changes had regional differences within the MOB. Our results suggest that NIRS technology might be a useful tool to identify of various odorants in a non-invasive manner using animals which has a superb olfactory system.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Bulbe olfactif
/
Oxygène
/
Dérivés du benzène
/
Hémoglobines
/
Spectroscopie proche infrarouge
/
Hémodynamique
/
Cétones
/
Odorisants
Limites du sujet:
Animaux
langue:
Anglais
Texte intégral:
Experimental Neurobiology
Année:
2011
Type:
Article
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