Progress in the diagnosis and treatment of hepatopulmonary syndrome in children / 国际儿科学杂志

ABSTRACT

Hepatopulmonary syndrome (HPS) is a group of rare and serious complications caused by liver disease,which is summarized as "progressive chronic liver disease,pulmonary vasodilatation,abnormal gas exchange leading to arterial hypoxemia".Progressive hypoxemia causes high mortality in children with HPS,and liver transplantation is the only effective cure method.At present,there are few research on HPS in children,especially in China.The possible etiology,pathogenesis,clinical characteristics,diagnosis and detection methods,treatment and prognosis are reviewed in this paper.