Latest study progress of umbilical cord-derived mesenchymal stem cells treating neonatal hypoxic-ischemic brain damage / 中华实用儿科临床杂志

ABSTRACT

Severe neonatal hypoxic-ischemic encephalopathy (HIE)can result in serious outcomes including death during the newborn period and permanent neuropsychological handicaps in the form of cerebral palsy,learning disability,epilepsy and so on.So far,there have been no effective treatments in clinical practice.Stem cell transplantation therapy brings new hope for HIE treatment.Among them,umbilical cord-derived mesenchymal stem cells have many advantages such as rich source,easy collection,shorter doubling time,lower immunogenicity and long-term survi-val after transplantation,it will have a broad application prospects as a cell source for the treatment of neonatal HIE.