Anti-myelin oligodendrocyte glycoprotein antibody and central nervous system immune demyelinating diseases / 中华实用儿科临床杂志

ABSTRACT

Myelin oligodendrocyte glycoprotein (MOG) is a component of central nervous system myelin.Anti-MOG antibodies are important in both pediatric and adult demyelination and the clinical association of MOG antibody-induced demyelination has been refined to include neuromyelitis optica spectrum disease,optic neuritis,and acute disseminated encephalomyelitis.But there are still many questions about epidemiological,clinical,radiological,and prognostic profile in patients with MOG antibody-associated demyelination.No consensus has been reached on detecting this antibody.This review will summarize the advances in anti-Myelin oligodendrocyte glycoprotein antibody.