Reflection and future of immunotherapy for type 1 diabetes mellitus / 中国医师杂志

ABSTRACT

Type 1 diabetes mellitus (T1DM) is a chronic autoimmune disease with an increasing prevalence and affects quality of life.Daily insulin replacement therapy is not a radical treatment.With the progress of the disease course,it is often accompanied by a variety of complications and has a high rate of disability and mortality.Many breakthroughs have been made in the prevention and treatment of type 1 diabetes through immune intervention,but clinical trials that have always failed to achieve the desired results have led scientists to rethink where immunotherapy should go in the future.