Identification of melatonin receptor in human embryonic peripheral tissue / 第二军医大学学报
Academic Journal of Second Military Medical University
;
(12): 8-11, 2001.
Article
Dans Chinois
| WPRIM
| ID: wpr-735321
ABSTRACT
Objective:
To determine protein binding characteri stic and signal transmission pathway of melatonin(Mel) receptor(MR) in human e mbryonic peripheral organ tissues.Methods:
MR was measured by radio ligand-binding assay and the effect of GTPγS on melatonin specific bindi ng was studied.Results:
Mel specific binding sites were det ermined in 16 kinds of human embryonic tissue and this binding could be inhibit ed by GTPγS, supporting the theory that MR is coupled to inhibitory G-proteins system.Conclusion:
MR is measured in human embryo tissue, the se results provide experimental data for elucidating the mechanism of the effect of Mel.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Type d'étude:
Etude diagnostique
langue:
Chinois
Texte intégral:
Academic Journal of Second Military Medical University
Année:
2001
Type:
Article
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