Comparison of application of Cochran-Armitage trend test and linear regression analysis for rate trend analysis in epidemiology study / 中华流行病学杂志

ABSTRACT

We described the time trend of acute myocardial infarction (AMI) from 1999 to 2013 in Tianjin incidence rate with Cochran-Armitage trend (CAT) test and linear regression analysis,and the results were compared.Based on actual population,CAT test had much stronger statistical power than linear regression analysis for both overall incidence trend and age specific incidence trend (Cochran-Armitage trend P value＜linear regression P value).The statistical power of CAT test decreased,while the result of linear regression analysis remained the same when population size was reduced by 100 times and AMI incidence rate remained unchanged.The two statistical methods have their advantages and disadvantages.It is necessary to choose statistical method according the fitting degree of data,or comprehensively analyze the results of two methods.