Critical effects of long non-coding RNA on fibrosis diseases
Experimental & Molecular Medicine
;
: e428-2018.
Article
Dans Anglais
| WPRIM
| ID: wpr-739497
ABSTRACT
The expression or dysfunction of long non-coding RNAs (lncRNAs) is closely related to various hereditary diseases, autoimmune diseases, metabolic diseases and tumors. LncRNAs were also recently recognized as functional regulators of fibrosis, which is a secondary process in many of these diseases and a primary pathology in fibrosis diseases. We review the latest findings on lncRNAs in fibrosis diseases of the liver, myocardium, kidney, lung and peritoneum. We also discuss the potential of disease-related lncRNAs as therapeutic targets for the clinical treatment of human fibrosis diseases.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Anatomopathologie
/
Péritoine
/
Maladies auto-immunes
/
Fibrose
/
ARN long non codant
/
Maladies génétiques congénitales
/
Rein
/
Foie
/
Poumon
/
Maladies métaboliques
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Experimental & Molecular Medicine
Année:
2018
Type:
Article
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