Clinical Safety and Efficacy of Autologous Bone Marrow-Derived Mesenchymal Stem Cell Transplantation in Sensorineural Hearing Loss Patients
Journal of Audiology & Otology
;
: 105-109, 2018.
Article
Dans Anglais
| WPRIM
| ID: wpr-740320
ABSTRACT
Stem cell transplantation represents a promising therapy for several degenerating and necrotic diseases. In several animal studies, we could find hearing restoration after inoculation of the mesenchymal stem cells' as well as mesenchymal stem cells' differentiation of hair cells and spiral ganglion. But until now, no clinical study has been reported directly for the human being. In this pilot studies, we applied mesenchymal stem cells to human beings trans-venously. Although we verified the safety of the autologous bone marrow stem cell transplantation in sensorineural hearing loss patients but we could not achieve significant improvement in hearing.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Moelle osseuse
/
Projets pilotes
/
Ganglion spiral
/
Transplantation de cellules souches
/
Transplantation de cellules souches mésenchymateuses
/
Stimulation électrique
/
Cellules souches mésenchymateuses
/
Étude clinique
/
Poils
/
Ouïe
Limites du sujet:
Animaux
/
Humains
langue:
Anglais
Texte intégral:
Journal of Audiology & Otology
Année:
2018
Type:
Article
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