Your browser doesn't support javascript.
loading
A Case of Pulmonary Alveolar Proteinosis Improved with Inhaled Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) / 대한내과학회지
Korean Journal of Medicine ; : 357-361, 2012.
Article Dans Coréen | WPRIM | ID: wpr-741075
ABSTRACT
Pulmonary alveolar proteinosis (PAP) is a rare lung disease characterized by the accumulation of lipoproteinaceous material within the alveoli. Several studies have recently found that autoantibodies against granulocyte-macrophage colony-stimulating factor (GM-CSF) play a major role in the pathogenesis of idiopathic PAP. Consequently, inhaled or systemic injection of GM-CSF has been suggested as a promising treatment for PAP. A 54-year-old male visited our hospital for progressive dyspnea. Four years earlier, he was diagnosed with PAP based on a surgical lung biopsy in another institution. Whole-lung lavage was performed four times before he visited our hospital. We administered high-dose inhaled GM-CSF therapy for 12 weeks followed by 12 weeks of low-dose therapy. After the GM-CSF treatment, the patient's symptoms, lung function, and radiological findings were improved significantly.
Sujets)

Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Protéinose alvéolaire pulmonaire / Autoanticorps / Biopsie / Administration par inhalation / Facteur de stimulation des colonies de granulocytes et de macrophages / Dyspnée / Irrigation thérapeutique / Poumon / Maladies pulmonaires Limites du sujet: Humains / Mâle langue: Coréen Texte intégral: Korean Journal of Medicine Année: 2012 Type: Article

Documents relatifs à ce sujet

MEDLINE

...
LILACS

LIS

Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Protéinose alvéolaire pulmonaire / Autoanticorps / Biopsie / Administration par inhalation / Facteur de stimulation des colonies de granulocytes et de macrophages / Dyspnée / Irrigation thérapeutique / Poumon / Maladies pulmonaires Limites du sujet: Humains / Mâle langue: Coréen Texte intégral: Korean Journal of Medicine Année: 2012 Type: Article