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Serologic Tests of IgG and IgM Antibodies and IgG Avidity for Diagnosis of Ocular Toxoplasmosis
The Korean Journal of Parasitology ; : 147-152, 2018.
Article Dans Anglais | WPRIM | ID: wpr-742238
ABSTRACT
This prospective study was aimed to detect acute and chronic ocular toxoplasmosis by comparison of anti-Toxoplasma gondii IgM and IgG antibody levels and IgG avidity test. One hundred and seventeen patients with ocular toxoplasmosis (OT) who referred to the Farabi Eye Hospital, Tehran, Iran were included in this study. Of the patients, 77 cases were positive for anti-T. gondii IgG, and 8 cases were positive for anti-T. gondii IgM. IgG avidity test revealed 11, 4, and 102 cases were low, intermediate, and high, respectively, and 6.8% and 9.4% of cases were positive for IgM and IgG avidity tests, respectively (P=0.632). Agreement (Kappa value) between paired tests IgG-IgM, IgG-IgG avidity, and IgM-IgG avidity was 0.080, 0.099, and 0.721, respectively (P < 0.05). This study showed that conventional serologic tests (IgM and IgG levels) and IgG avidity correlate well each other and can be used to differentiate recent infections from old OT. It seems that reactivated old infections rather than recently acquired infections are majority of Iranian OT patients.
Sujets)

Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Toxoplasma / Immunoglobuline G / Immunoglobuline M / Tests sérologiques / Toxoplasmose oculaire / Études prospectives / Diagnostic / Iran / Anticorps Type d'étude: Etude diagnostique / Étude observationnelle Limites du sujet: Humains Pays comme sujet: Asie langue: Anglais Texte intégral: The Korean Journal of Parasitology Année: 2018 Type: Article

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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Toxoplasma / Immunoglobuline G / Immunoglobuline M / Tests sérologiques / Toxoplasmose oculaire / Études prospectives / Diagnostic / Iran / Anticorps Type d'étude: Etude diagnostique / Étude observationnelle Limites du sujet: Humains Pays comme sujet: Asie langue: Anglais Texte intégral: The Korean Journal of Parasitology Année: 2018 Type: Article