The effects of full marathon on hemodynamics related to cardiac electrophysiology of marathon amateurs / 中华急诊医学杂志

ABSTRACT

Objective To observe and assess the effects of full marathon on hemodynamics and cardiac electrophysiology of marathon amateurs without adverse event after the race.Methods Fiftyone subjects were included in the final analysis of the study,blood pressure,heart rate,body surface electrocardiogram (ECG) of all subjects under static status before the race and within (15-30) min after the race were detected,and sufficient amounts of the peripheral blood and the radial arterial blood specimens of all subjects under static status before the race and within (15-30) min after the race were collected instantly.The peripheral blood was used for measuring markers of muscle injury and NT-proBNP,and the radial arterial blood was taken for blood gas analysis.The QTc interval,QRS,PR interval,and QTd interval were recorded from the 12-lead ECG report.Results Compared with those under static status before the race,the systolic blood pressure,diastolic blood pressure,mean arterial blood pressure and heart rate of all the subjects within (15-30) min after the race were significantly higher (P＜0.05).When the markers of striated muscle injury were compared before and after the competition,levels of CK,cTNI,LDH,and myoglobin after the race were significantly increased compared with them under static status before the race (P ＜0.05),and the level of NT-proBNP after the race was also significantly increased compared with it before the race (P＜0.05).When blood gas analysis before the race was compared with that after the race,the PH values after race were significantly lower than it before race (P＜0.05).The level of lactic acid after the race was significantly higher than it before race (P＜0.05).After the race,the levels of PCO2,SBE and HCO3-decreased significantly compared with those before race (P＜0.05),and the QTc and QTd intervals after the race increased significantly compared with those before the race,however,the QTc interval and QTd interval for all subjects before and after the competition were within the normal range.Conclusions Full marathon significantly affect the myocardial electrophysiological markers of healthy amateur athletes without chronic diseases,but those markers fluctuate within the normal range.