Two Cases of Wernicke's Encephalopathy That Developed during Total Parenteral Nutrition in Colon Cancer Patients Treated with 5-Fluorouracil-based Chemotherapy / 대한소화기학회지
The Korean Journal of Gastroenterology
; : 158-163, 2014.
Article
de Ko
| WPRIM
| ID: wpr-74442
Bibliothèque responsable:
WPRO
ABSTRACT
Wernicke's encephalopathy (WE) caused by thiamine deficiency is an acute neurological disorder. Clinically, the classic triad of WE consists of ophthalmoplegia, ataxia, and mental status changes. Thiamine deficiency is known to occur commonly in chronic alcoholic patients. Sometimes, it can occur in patients after gastrointestinal surgery and in those with malabsorption. In addition, patients undergoing renal dialysis, suffering from hyperemesis gravidarum, receiving total parenteral nutrition (TPN), and being treated with chemotherapeutic agents are also prone to develop thiamine deficiency. Herein, we report two cases of WE that developed following simultaneous 5-fluorouracil (5-FU) chemotherapy and TPN in colon cancer patients which was successfully treated with thiamine administration.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Thiamine
/
Complexe vitaminique B
/
Encéphalopathie de Gayet-Wernicke
/
Encéphale
/
Imagerie par résonance magnétique
/
Nutrition parentérale totale
/
Tumeurs du côlon
/
Fluorouracil
/
Antimétabolites antinéoplasiques
Limites du sujet:
Adult
/
Humans
/
Male
langue:
Ko
Texte intégral:
The Korean Journal of Gastroenterology
Année:
2014
Type:
Article