Relationship between depressive symptoms andblood biochemical indices in elderly inpatients / 中国心理卫生杂志

ABSTRACT

Objective:To investigate the relationship between the depressive symptoms and blood biochemical indexes in elderly inpatients.Methods:Totally 201 inpatients without depression were enrolled in this study.Blood tests and the Geriatric Depression Scale-5 (GDS-15) were performed on all of the patients.The patients were divided into non-depressive symptoms group and depressive symptoms group according to GDS-15 score.Differences between two groups were compared, and multiple linear regression analysis was used to screen for risk factors by SPSS 22.0.Results:Serum total protein (TP) [ (60.7±4.3) vs. (63.5±5.6) g/L] and hemoglobin [ (121.6±20.1) vs. (129.7±19.4) g/L] were lower in the depressive symptoms group than in the non-depressive symptoms group (Ps＜0.05).There were no differences between the two groups in age, BMI, fasting blood glucose, total cholesterol, triglyceride, high density lipoprotein cholesterol and low density lipoprotein cholesterol (Ps＞0.05).Multiple linear regression analysis showed that TP was the predictive variable for GDS-15 score (β=-0.4, P＜0.05).Conclusion:Serum total protein and hemoglobin levels in patients with depressive symptoms may be significant lower than those in patients without depressive symptom.There is association between serum total protein and depressive symptoms.