Human Transcriptome and Chromatin Modifications: An ENCODE Perspective
Genomics & Informatics
;
: 60-67, 2013.
Article
Dans Anglais
| WPRIM
| ID: wpr-74508
ABSTRACT
A decade-long project, led by several international research groups, called the Encyclopedia of DNA Elements (ENCODE), recently released an unprecedented amount of data. The ambitious project covers transcriptome, cistrome, epigenome, and interactome data from more than 1,600 sets of experiments in human. To make use of this valuable resource, it is important to understand the information it represents and the techniques that were used to generate these data. In this review, we introduce the data that ENCODE generated, summarize the observations from the data analysis, and revisit a computational approach that ENCODE used to predict gene expression, with a focus on the human transcriptome and its association with chromatin modifications.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
ADN
/
Chromatine
/
Expression des gènes
/
Statistiques comme sujet
/
Transcriptome
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Genomics & Informatics
Année:
2013
Type:
Article
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