Clinical characteristics of hospitalized elderly female heart failure patients with preserved ejection fraction / 中华老年心脑血管病杂志

ABSTRACT

Objective To analyze the clinical characteristics of hospitalized elderly female heart failure( HF)patients with preserved ejection fraction.Methods One hundred and sixty-eight≥65 years old hospitalized female HF patients admitted to our hospital from 2016-04-01to 2017-03-31 were divided into elderly HF with preserved ejection fraction(HFpEF)group(n=136)with their LVEF≥40％and HF with reduced ejection fraction(HFrEF)group(n=32)with their LVEF＜ 40％).Their clinical characteristics were retrospectively analyzed.Results The age was significantly older,the BMI,SBP and incidence of AF and anemia were significantly higher in HFpEF group than in HFrEF group(76.44±7.28year vs 72.47±8.19years,25.11±3.34kg/m2 vs 22.95±3.53kg/m2,140.49±20.77mm Hg vs 131.09±19.96mm Hg,44.1％vs 25.0％,22.1％vs 6.3％,P＜0.05,P＜0.01).The main cause of HF was hypertension(85.3％)in HFpEF group.The serum creatinine,UA,potassium,NT-proBNP levels were significantly lower,the heart rate was significantly slower,the QT and QRS intervals were significantly shorter,the incidence of ventricular arrhythmia was significantly lower,the LVEDD,LVESD,LA and pulmonary artery diameter were significantly shorter while the serum sodium level was significantly higher and the interventricular septum was significantly thicker in HFpEF group than in HFrEF group(P＜0.05,P＜0.01).The ratio of CCB therapy was significantly higher while the ratios of angio-tension converting enzyme inhibitor/angiotensionⅡreceptor antagonist therapy,diuretics therapy,beta-blockers therapy,digitalis therapy and lipid-lowering drug therapy were significantly lower in HFpEF group than in HFrEF group(P＜0.05,P＜0.01).Conclusion The age is older,the BMI and incidence of hypertension,AF and anemia are higher in hospitalized elderly HF female patients with preserved ejection fraction.