A review on evaluating application of abnormal iron deposition in brain on diagnosis and differential diagnosis of Parkinson's disease / 中华老年医学杂志

ABSTRACT

Parkinson's disease (PD)is a common neurological degenerative diseases,and its diagnosis mainly depends on a patient's clinical manifestations and the response to dopaminergic drugs.The coincidence rate between clinical diagnosis and pathological diagnosis for PD is only 70％-80％.It is found that abnormality of intracranial iron deposition is one of the important pathological changes in PD progression.Therefore,it can be helpful to detect the abnormal iron deposition in brain using MRI and Doppler sonography for early diagnosis and differential diagnosis of PD.